Crystal structure of native chicken fibrinogen with two different bound ligands
Изображения по теме:
Crystal structure of native chicken fibrinogen at 2.7 A resolution.
Blood Clotting
PDB: 1M1J
Morph conformations
Docking |
The stereochemistry of the protein myoglobin
Изображения по теме:
The stereochemistry of the protein myoglobin.
Oxygen Storage
PDB: 1MBN
Morph conformations
Docking |
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Atomic structure of the actin:DNASE I complex
Изображения по теме:
Atomic structure of the actin:DNase I complex.
Endodeoxyribonuclease
PDB: 1ATN
Rotating model: 1, 2
Docking and conformation:
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Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains
Изображения по теме:
Hormone/growth Factor Receptor
PDB: 1DKF
Morph Conformation: 1, 2
Docking:
- OLA (Oleic acid): 1, 2
- BMS: 1, 2, 3
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Structure of Aspirin Acetylated Cyclooxygenase-1 in Complex with Diclofenac
Изображения по теме:
Oxidoreductase
Comparison of cyclooxygenase-1 crystal structures: cross-talk between monomers comprising cyclooxygenase-1 homodimers.
PDB: 3N8Y
Ligand Binding: 1, 2
Docking:
- BMA (Beta-D-Mannose): 1, 2, 3
- BOG (B-Octylglucoside): 1, 2
- DIF (Diclofinac): 1, 2
- HEM (Protoporphyrin IX): 1, 2
- SAL (Salicylic acid): 1, 2
- NDG: (2-(Acetylamino)-2-Deoxy-a-D-Glucopyranose): 1, 2
- NAG (N-acetyl-D-glucosamine): 1, 2
- MAN (Alpha-D-Mannose): 1, 2
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Structure of HIV-1 protease bound to atazanavir
Изображения по теме:
Hydrolase
Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir.
PDB: 2AQU
Structure components: 1, 2, 3
Surface
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HIV-1 proteinase complexed with RO 31-8959
Изображения по теме:
Hydrolase/hydrolase Inhibitor
Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere.
PDB: 1HXB
Ligand binding
Morph conformation
Saquinavir docking: 1, 2
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Structure of the human anaplastic lymphoma kinase in complex with crizotinib (PF-02341066)
Изображения по теме:
Transferase
Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).
PDB: 2XP2
Conformation and ligand binding
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Piracetam bound to the ligand binding domain of GluA2
Изображения по теме:
Transport Protein
Piracetam defines a new binding site for allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors.
PDB: 3LSF
Docking
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Vildagliptin
Изображения по теме:
Anti-diabetic drug
ChemSpider: 5293734
Rotating model
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Aniracetam bound to the ligand binding domain of GluA3
Изображения по теме:
Transport Protein
Piracetam defines a new binding site for allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors.
PDB: 3LSW
Ligand Binding
Docking
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Piracetam bound to the ligand binding domain of GluA2
Изображения по теме:
Transport Protein
Piracetam defines a new binding site for allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors.
PDB: 3LSF
Docking
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R6 human insulin hexamer (symmetric), NMR, 10 structures
Изображения по теме:
Hormone
Solution structures of the R6 human insulin hexamer.
PDB: 1AIY
Morph conformation
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Collagen
Изображения по теме:
Structural Protein
Sequence dependent conformational variations of collagen triple-helical structure.
PDB: 1BKV
Conformation and docking
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Deoxy RHB1.2 (recombinant hemoglobin)
Изображения по теме:
Oxygen Storage/transport
Genetically crosslinked hemoglobin: a structural study.
PDB: 1C7D
Conformation
Docking
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Crystal structure of the nuclear receptor for vitamin D complexed to vitamin D
Изображения по теме:
Gene Regulation
The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand.
PDB: 1DB1
Docking
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Structure of human oxyhaemoglobin at 2.1 angstroms resolution
Изображения по теме:
Oxygen Transport
Structure of human oxyhaemoglobin at 2.1 A resolution.
PDB: 1HHO
HEM docking: 1, 2, 3
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